Crispr Therapeutics is an emerging gene editing company focused on the development of Crispr/Cas9-based therapeutics. The company's proprietary platform specializes in clustered regularly interspaced ...

Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.

To discover factors in repair of genomic uracil, we performed a CRISPR knockout screen in the presence of floxuridine, a chemotherapeutic agent that incorporates uracil and fluorouracil into DNA. We ...

All experiments were performed in triplicate. The pLenti-CRISPR-V2 vector was used for CRISPR/Cas9-mediated gene knockout in CAL27 and FaDu cell lines. Briefly, lentivirus vector expressing CASP3 gRNA ...