A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...
A UCO team has applied the genome editing technique, which garnered a Nobel Prize in Chemistry in 2020, to unravel the ...
This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...
When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...
Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...
Gene knockout models involve the deliberate inactivation ... protein 9 systems are common gene-editing technologies, with ...
CRISPR Therapeutics AG is a gene editing company, which engages in the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform.