Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

(REUTERS) British scientists are testing cutting edge gene editing techniques in mice, by inserting a jelly fish gene that makes their skin green. The research uses CRISPR-Cas9, a gene editing ...

A minimum of 3 positive founders will be delivered. To produce CRISPR/cas9-mediated gene indels to generate knock-out mice or rats. The investigator will provide or purchase the CRISPR gRNA(s). TGEF ...

The paper L. Jubair et al., “Systemic delivery of CRISPR/Cas9 targeting HPV oncogenes is effective at eliminating established tumors,” Mol Ther, 27:2091–99, 2019. When the human papillomavirus enters ...

A new study in mice documents frequent undesirable repeats of DNA insertions ... In less than a decade since its adaptation to a genome-editing technique, CRISPR-Cas9 has been used on lab animals and ...

“We identified the genetic basis for this coat color variation using a combination of field ecological data, population genomic data, and a CRISPR–Cas9 knockout mouse model,” the study mentione ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas ... Now, an in vivo protocol facilitates screens in mouse brain, using adeno-associated virus with transposon-based delivery of the CRISPR ...

knock-out, knock-in and gene-edited mice and rats. We offer pronuclear injection of DNA into zygotes, gene targeting in ES cells and pronuclear or cytoplasmic injection as well as zygote ...