The company’s CRISPR/Cas9 is a revolutionary technology for gene editing which is the process of precisely altering specific sequences of genomic DNA. It has a portfolio of therapeutic programs ...

In contrast to paediatric and adult organoids, fetal gut-derived organoids showed distinct dynamic changes of DNA methylation and gene expression in culture, indicative of an in vitro maturation. By ...

From a translational perspective, the results from this first-in-human clinical trial have important implications, because they underline the feasibility of using CRISPR-Cas9-engineered TILs in ...

The incomplete annotation of mitochondrial proteins highlights the need for a comprehensive gene inventory, particularly for Oxidative Phosphorylation (OXPHOS). To address this, we developed a ...

Crispr Therapeutics is an emerging gene editing company focused on the development of Crispr/Cas9-based therapeutics. The company's proprietary platform specializes in clustered regularly ...

In a new study published in Nature titled, “Custom CRISPR ... Cas9 enzyme design, the MGH group performed selective targeting of the P23H mutation of rhodopsin in human cells and mice.

"Our study is a first step in dramatically expanding our repertoire of effective and safe CRISPR-Cas9 enzymes ... in primary human cells and in mice," said corresponding author Ben Kleinstiver ...

For the first time, a team of researchers has shown that they can remove HIV type 1 (HIV-1) from infected mouse cells using a powerful gene-editing ... researchers used CRISPR/Cas9, a tool that ...