Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas ... Here, the authors present dFLASH; a dual FLuorescent transcription factor Activity Sensor for Histone-integrated live-cell reporting for ...

To obtain high densities of sgRNA that would give signals significantly above the intracellular fluorescent background, especially when the chromatin is in open state during G and S phases ...

Knocking in genes allows scientists to study the effects of specific gene variants, to use reporter genes like green fluorescent protein to track ... an MD/PhD candidate at the University of ...

In a new development, researchers have successfully created an efficient two-line system for hybrid seed production in ...

Taking note of this, Pia and his colleagues used the CRISPR-Cas9 technology, which targets SOX2. CRISPR-Cas9 is like a pair of scissors that can cut specific genes in DNA and is known to be able ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

Procko grew Venus flytrap plants in tissue culture and then fired gold particles covered with plasmid DNA containing components of the CRISPR-Cas9 system into the cells. In the plasmid, the ...

Various strategies have been developed to enhance the imaging capabilities of CRISPR/Cas9. One approach involves fusing fluorescent proteins to deactivated Cas9 (dCas9), allowing for the ...

The recent discovery of CRISPR/Cas9 technology simplified engineering synthetic gene drives for diverse animal species. Nowadays, synthetic gene drives have been engineered in laboratory mosquitoes ...

The agreement grants Jumpcode access to ERS' CRISPR/Cas9 patent portfolio, empowering the company to advance the sensitivity and efficiency of next-generation sequencing (NGS) and expand ...