CRISPR-edited iPSCs uncover early mitochondrial defects shared across ALS mutations, revealing pathways that could guide future treatments.

For years, the CRISPR-Cas9 genome technology has been reshaping genetic engineering, a precision tool to transform everything ...

The CRISPR-Cas9 patent landscape remains complex and unsettled. The Federal Circuit’s latest decision in University of California v.

Gene-edited spiders had never been seen before. Then University of Bayreuth researchers used CRISPR Cas-9 to give spiders red ...

The only gene-editing therapy currently on the market is a CRISPR–Cas9-based treatment for two blood disorders, sickle-cell ...

Researchers at UC Berkeley’s Innovative Genomics Institute, or IGI, developed a revolutionary treatment using CRISPR gene ...

CRISPR-Cas9 is a powerful gene editing system that has revolutionized our ability to treat disease and probe the human genome. CRISPR has been used to edit the genomes of animals, plants, and microbes ...

Using the gene scissors CRISPR and stem cells, researchers at Stockholm University and the UK Dementia Research Institute (UK ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Casgevy (exagamglogene autotemcel or exa-cel) became the first drug based on the CRISPR/Cas9 gene-editing technology to be approved towards the end of last year, when it was cleared by the FDA for ...

No AAV9 capsid or Cas9 transgene–specific T-cell responses ... precluded assessment of the safety and efficacy of the CRISPR–transactivator approach. Although trace amounts of the transgene ...