Lorundrostat is in a new class of blood pressure medications called aldosterone synthase inhibitors (ASIs). Several ASIs are currently in development and are designed to work by disrupting the ...

For instance, CRISPR-Cas9-mediated knockout of PD-1 in CAR-T cells targeting IL13Rα2 resulted in increased T-cell persistence and anti-tumor activity in GBM models. In addition, the immunosuppressive ...

A Peninsula biotech company raised $68 million from investors — including a venture philanthropy fund started by Lululemon Athletica founder Chip Wilson — to push a next-generation CRISPR drug ...

EPI-321, the startup’s lead program, uses CRISPR tools to stop errant expression of a gene implicated in the muscle-wasting condition. Epicrispr will start a Phase 1 trial this year in New Zealand, ...

FZU - Institute of Physics of the Czech Academy of Sciences, 182 21 Prague, Czech Republic Faculty of Mathematics and Physics, Charles University, Ke Karlovu 3, 121 16 Prague 2, Czech Republic FZU - ...

In a separate study presented at ACC.25, researchers from a different group reviewed the scientific literature and found that studies showed a strong correlation between microplastics in plaques in ...

A dramatic, and somewhat chaotic, weekend of ACC baseball is over. Similar to last week, there are seven teams in the USA Today Coaches Poll, with No. 25 Georgia Tech entering the poll and ...

Methods: NEU1 expression in liver cancer was evaluated using public databases and validated in our samples. CRISPR/Cas9, CCK-8 assay, transwell assays, oil red O staining, RNA-sequencing, ...

The ACC hoped that North Carolina's win over San Diego State was the start of something big, something we have seen before in March Madness. On several occasions in recent years, the ACC had a ...

The board of ACC has commissioned an independent review into the agency's workplace culture. It follows investigations by Stuff, which revealed concerns over the behaviour of two deputy chief ...