highlighted critical CF/CM-specific cis-regulatory elements (CRE) such as enhancers and TFs to regulate gene ... The epigenetic landscape between these two cell types is not solely dependent on ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room ...

Researchers at Tel Aviv University have announced that they have successfully removed half of a tumor in a mouse's head using ... Aviv University was to use CRISPR-Cas9 to remove the protein ...

Researchers have developed a machine learning model that predicts Cas9 proteins that can be tailored with designer properties for therapeutic use.

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system ...

Mice with active infections had EcoHIV, the mouse equivalent of human HIV-1. Using CRISPR/Cas9, researchers were able to block replication of the virus and show they could potentially prevent ...

In this study, we demonstrated the exploitation of CRISPR/Cas9 as a high precision system for editing the ... in line with published mouse models also reporting a lack of endochondral ossification and ...

Here, we identify S100PBP as a key modulator of both XY and autosomal recombination in mice. S100pbp-knockout mice exhibit male ... to the nuclear pores of meiocytes, likely in a TPR-dependent manner.