Mesenchymal stem cells (MSCs), or multipotent mesenchymal stromal cells as they are also known, have been identified in bone marrow as well as in other tissues of the joint, including adipose ...

Through the team's efforts, researchers and doctors now have a much clearer picture of the functions of the rarer but key cells in the bone marrow such as stromal cells, bone cells, and ...

Ground zero for the protective activity was not the hematopoietic stem cells themselves, but the bone marrow stroma, a ...

The contribution of molecular alterations in bone marrow mesenchymal stromal cells (BM-MSC) to the pathogenesis of acute myeloid leukemia (AML) is poorly understood. Thus we assessed genome-wide ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Types of Bone Metastatic Tumors Cytokines secreted by DTCs stimulate osteoclastogenesis. DTCs also co-opt stromal and blood cells of the marrow to induce osteolysis. DTCs can activate osteomimicry ...

Discover how blood stem cells release IL-10 to regulate inflammation and protect bone marrow, offering new therapeutic ...