In silico activities are displayed in orange, biophysical screening activities are displayed ... within the BRPF1b active site (grey cartoon, PDB = 6EQK). Key residues are represented in grey ...

Recent advances in biophysical screening technology have made the detection of binding events associated with the smallest of fragments possible. Often the biological target of interest has been ...

AnPac is a China-focused cancer screening company that designs and manufactures devices that analyze the biophysical properties of blood to determine an individual’s risk of cancer. It is also ...

The authors say that studies using biophysical screening are needed to determine whether treatment based on screening test results is beneficial. They write, "For a first-trimester risk assessment ...

This protocol describes the screening of a library of low-molecular-weight compounds (fragments) using a series of biophysical ligand-binding assays. Fragment-based drug discovery (FBDD ...