Machine learning and supercomputing have brought about a revolution in computational drug discovery. More therapeutic ...

Dynamic light scattering is frequently utilized to assess the quality of protein aggregation ... the presence of several binding species generates binding curves that cannot correctly fit under ...

Evotec's insights into GPCRs and waveRAPID technology reveal new opportunities in drug discovery, focusing on orphan ...

Figure 2: ThT and curcumin rescue a paralysis phenotype and slow protein aggregation in vivo ... The first day of adulthood is day 3 in survival curves. We noted between-experiment variation ...

The work demonstrates a transformative step forward in profiling protein expression ... The implementation of CuRVE in this study integrates innovations that control antibody binding speed and ...

A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that ...

From drug discovery to protein research, the MST assay is revolutionizing how scientists analyze binding affinities, making it a cornerstone of modern biophysical analysis. This article delves into ...

Sex hormone binding globulin (SHBG) is a protein in your blood that binds certain hormones. It’s produced in the liver and—in smaller amounts—in the testes. It’s an ancient protein that ...

Led by Ryan Flynn, MD, PhD, assistant professor of stem cell and regenerative biology at Harvard Medical School (HMS), the study identified one RNA-binding protein on the cell surface, NPM1 ...

Insulin resistance has a causal role in type 2 diabetes. Serum levels of retinol-binding protein 4 (RBP4), a protein secreted by adipocytes, are increased in insulin-resistant states. Experiments ...