Hepatic synthesis of bile acids is the primary pathway for cholesterol catabolism ... providing important spillover routes for bile acids and bilirubin. Consequently, bile-acid transporters ...

This is in part because lung cells can be driven to a profibrotic phenotype by multiple pathways that reinforce each other, so that targeting one pathway alone may not be effective to slow or stop ...

More frequent monitoring may be necessary for patients at risk for hyperkalemia, including those on concomitant medications that impair potassium excretion or increase serum potassium.

Presentations at the American College of Cardiology (ACC) 74 th Annual Scientific Session & Expo 2025 include 10 new prespecified subgroup analyses from FINEARTS-HF, the pivotal Phase III ...

Expert Rev of Obstet Gynecol. 2012;7(3):269-279. In summary, excess levels of urobilinogen and bilirubin in the urine may signal liver disease, and more research is needed to correlate these ...

Elevations in serum bilirubin during treatment with lapatinib and pazopanib are associated predominantly with UGT1A1*28 and Gilbert's syndrome. Gilbert's syndrome is clinically benign, so isolated ...

This title is part of a longer publication history. The full run of this journal will be searched. TITLE HISTORY A title history is the publication history of a journal and includes a listing of the ...

In the present work, an attempt was made to study the erythropoietic effect of cobalt first in hematologically normal patients. Then, especially because of the apparently successful results of ...

The following studies were done repeatedly during the hospital stay and remained within normal limits: erythrocyte sedimentation rate; stool guaiac test; serum electrolytes; serum bilirubin ...

What Are Inherited Metabolic Disorders? Inherited metabolic disorders are genetic conditions that result in metabolism problems. Most people with inherited metabolic disorders have a defective ...

A high bilirubin level, or hyperbilirubinemia, occurs when bilirubin has accumulated in your body in excessive amounts. Bilirubin forms when red blood cells break down at the end of their life cycle, ...