Aficamten was associated with improved peak oxygen uptake and a tolerable safety profile vs. metoprolol, a beta-blocker, in ...

The findings hint at why the ABYSS trial failed to show it was safe to stop beta-blockers after an MI in stable patients.

†Present address: Department of Analytical Chemistry, Institute of Food Analysis and Research (IIAA), University of Santiago de Compostela, 15782-Santiago de Compostela, Spain. Article Views are the ...

However, some factors may change the heart rate. Beta-blockers (BB) are substances that inhibit the β-adrenergic receptors, promoting a negative chronotropic action, observed at rest and during ...

beta blockers use, calcium channel blockers use, nitrates use and diuretics use). Cox models for primary and secondary outcomes were conducted with ACEI versus ARB status as covariate after adjustment ...

However, the impact of β-blockers in acute-phase management of TC remains uncertain. This study aimed to examine whether early β-blocker use in TC was associated with lower in-hospital mortality.

over the standard beta blocker metoprolol in patients with obstructive hypertrophic cardiomyopathy (HCM). According to InvestingPro data, the stock is currently trading near its Fair Value, with ...

over the standard beta blocker metoprolol in patients with obstructive hypertrophic cardiomyopathy (HCM). According to InvestingPro data, the stock is currently trading near its Fair Value ...

MAPLE-HCM met its primary endpoint, demonstrating a statistically significant improvement in peak oxygen uptake (pVO 2) from baseline to Week 24 for aficamten compared to metoprolol. The safety and ...

These medications may cause drowsiness, and are often taken at bedtime. Beta-blockers are medications that reduce heart rate and blood pressure by blocking the actions of the hormone adrenaline ...

Recent evidence from randomized controlled trials has provided compelling evidence to support the use of β blockers in most patients with heart failure due to systolic dysfunction. There is ...