Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ...

Coverage may be possible for sequences with physically and chemically similar amino acid substitutions (e.g., non-polar, polar, basic ... obtain for structure–function-defined antibodies ...

A research team led by a Duke professor recently developed a novel computational model to predict antibody structures, a significant breakthrough for disease prevention efforts. A study published ...

Antibodies usually have a Y-shaped structure, and these hypervariable regions are located in the tips of the Y, where they detect and bind to foreign proteins, also known as antigens. The bottom ...

but implying that receptor engineering is somehow translatable or as impactful therapeutically as engineering the antibody itself deflates the real basic science/biochemical impact of understanding ...

VITT antibodies feature an oligoclonal or monoclonal antibody profile with a remarkable degree of clonal identity of the light chains, 3,4 which results in a strikingly similar structure of the ...

1 The basic mechanism involves monoclonal antibodies affixing themselves to ... 4 This article considers the structure, mechanism of action, and evolution of three generations, clinical success ...

The Chief Justice of India, D. Y. Chandrachud compared the ‘basic structure’ of the Constitution to the North Star, an unfailing guide which shows the way when the path appears convoluted.

Peptide mapping of antibodies is an essential method to monitor peptide ... The MAM approach allows scientists to confirm the primary structure of peptides, identify possible post-translational ...

Without advanced technology, figuring out the structure or shape of a single protein composed of 100 basic units (amino acids ... has used AlphaFold to help develop an antibody (a type of protein) ...

What was known, however, is that the structure between the antibody arms, the so called hinges, changes over time. This latest research harnesses this property of the hinge and explains how it ...

The involvement of Myelin Basic Protein (MBP) in Multiple Sclerosis (MS ... In this work we investigate the importance of the helical structure in antibody recognition by MBP peptides of different ...