Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

The following is a summary of “Identification of molecular clusters and a risk prognosis model for diffuse large B-cell lymphoma based on lactate metabolism-related genes,” published in the April 2025 ...

The phase I EXCELERIZE dose-escalation study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of REC-3565 for treating R/R B-cell lymphomas in ...

Approximately 41,000 relapsed and/or refractory (R/R) patients with CLL and B-cell lymphomas in the U.S. and EU5 are eligible for treatment each year.

The third time might be the charm for him after he received a refined therapy that trains his own immune cells to attack his particular lymphoma, but without much of the harsh side effects that ...

These findings suggest this unique cell therapy approach has promise for specific patients with lymphoma, but it may be adapted for more cancer types in the future. "We observed rapid and strong ...

ABSTRACT: Extra-nodal Non-Hodgkin’s Lymphomas (NHL) in the head and neck region are most commonly found in the Waldeyer’s lymphatic ring. However, Non-Hodgkin’s Lymphomas occurring in infra-temporal ...

Primary large B-cell lymphomas of immune-privileged sites (IP-LBCLs) include primary central nervous system large B-cell lymphoma (PCNSL), primary vitreoretinal large B-cell lymphoma (PVRL), and ...

Background: Tirabrutinib is a potent, irreversible, and highly selective Bruton’s tyrosine kinase (BTK) inhibitor that has demonstrated significant therapeutic activity in patients with relapsed or ...