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Lantern Pharma (LTRN) announced that a heavily pretreated patient with aggressive Grade 3 non-germinal center B-cell diffuse large B-cell lymphoma ...
Enzymes, such as γ-secretase, are able to cleave and release the extracellular domain of BCMA into the bloodstream as soluble ...
This action can lead to increased B-cell responses and IgG production. 4 These FcRn-regulated cellular pathways are involved in tissue responses that are associated with autoimmune diseases, as ...
15d
News Medical on MSNTranscription factor T-bet regulates memory B cell subsets
Researchers describe six subsets of memory B cells — including one subset that produces the transcription factor T-bet. Using ...
Hairy-cell leukemia, a rare B-cell cancer driven by a BRAF mutation and manifesting with cytopenias and splenomegaly, is responsive to purine analogue chemotherapy and to BRAF inhibitors combined w ...
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