What's more, the study made sure to compare the results to those of diabetes medications like Metformin, noting that some ...

(PDCs) demonstrate tumor-selective delivery and potent anticancer activityPreclinical data show robust efficacy as ...

Pharmaceuticals announced updated clinical data from Part 1b of the ongoing DENALI clinical trial of azenosertib in patients with ...

BMS-986446, formerly PRX005, is a potential best-in-class antibody for the treatment of Alzheimer's disease that specifically targets a key epitope within the microtubule binding region or MTBR of ...

PYX-201 is a first-in-concept antibody-drug conjugate with a microtubule inhibitor payload that targets Extradomain-B Fibronectin (EDB+FN), a noncellular structural component within the tumor ...

Qing received her B. S. and Ph.D. in Biochemistry and Molecular Biology from ... During this time, she began to study the folding and assembly of the intrinsically disordered microtubule associated ...

Specifically, tau fragments containing the microtubule binding region and its adjacent C-terminal sequence wreaked havoc on synaptic plasticity when injected into rat brains. Scientists led by Michael ...

TEDC1 and TEDC2, functions in generating centriolar triplet microtubules, and that this is crucial for the proper formation of centriolar subdomains and the stability of centrioles throughout the cell ...

PHYSICOCHEMICAL characterization of components of flagella and cilia is essential for an understanding of the mechanisms underlying flagellar and ciliary movement. The so-called “9 + 2” fibres ...