B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction. One of the fundamental goals of basic biology ...

B-cell acute lymphoblastic leukemia (B-ALL) is the most common cancer in children, accounting for around 85% of pediatric ...

B-cell lymphoma doesn’t always cause symptoms ... On the other hand, targeted therapies focus on a specific interaction between cancer cells. One promising new treatment is a drug called ...

T cells, which are the frontline warriors in the battle against infections, have been a major focus of research. Regulatory T cells (Tregs) are specialized immune cells that have a challenging ...

A promising lead has emerged from examining the interaction between the tumor and immune cells, including CAR-T cells. It turns out that B-ALL tumors may take advantage of the body’s natural ...

A “complete eradication” of B cells with chimeric antigen receptor T-cell therapy is responsible for the long-term, drug-free remission from autoimmune diseases observed after treatment ...

They make antibodies -- proteins that fight viruses and bacteria. B cells normally can’t cross from your blood into your brain or spinal cord. If you have MS, some B cells enter your brain and ...

Those B cells can become malignant or cancerous, and so we treat B-cell cancers with CD19 CAR T-cell therapy. Those T cells are all now reprogrammed to fight and recognize the cancerous B cells ...

Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 T cells, teaching them how to mount lasting defenses after vaccination. The study was recently ...

Monoclonal B-cell lymphocytosis (MBL) is estimated to affect about 5–12% of people. It doesn’t cause symptoms and doesn’t require active treatment. However, a subtype called high-count MBL ...

No single cause accounts for all cases of B-cell lymphoma, and some people who get the condition have none of the known risk factors. In general, doctors think that the interaction of several ...