Zika virus uses host cell autophagy to suppress antiviral proteins AXL and TIM-1, enhancing its ability to infect without ...

Patients with vitiligo experience impacts on quality of life, emerging therapies offer promising prospects for more targeted ...

Excessive sequestration of KEAP1 into phase-separated p62 bodies under conditions of impaired autophagy drives persistent ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in ...

Researchers have identified how autophagy and chaperone-mediated autophagy (CMA) drive the unconventional secretion of PARK7, ...

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its ...

Overconsumption of animal-based protein raises IGF-1 levels—a growth hormone linked to increased risk of chronic disease, accelerated aging, and reduced cellular repair. While IGF-1 is essential in ...

The process of autophagy keeps cells healthy, helps protect against disease, and plays a big role when we exercise or fast by helping to provide energy and nutrients. For the present study ...

The drug was such a breakthrough in the fight against tropical parasitic diseases that two scientists who studied it won the Nobel Prize in 2015. The Food and Drug Administration has approved ...

Defects in the autophagy system lead to the accumulation ... NEAT1 could reverse these alterations in in vitro models of the disease, opening the door to the exploration of new therapeutic ...