The presence of autophagic structures in dying cells, in diverse organisms has implicated autophagy in the cell death process. Cell death is of paramount importance both for the development and ...

Additional mechanisms may include a role for autophagy in the regulation of cell death and proliferation, as shown in models of cardiac and lung diseases. In cancer, autophagy may prevent ...

Scientists now believe that autophagy itself can trigger cell death, although it may be a rare and highly specialized event. Autophagy is certainly known to play a role when tissues are formed ...

Autophagy also kills the cells under certain conditions. These are form of programmed cell death (PCD) and are called autophagic cell death. Programmed cell death is commonly termed apoptosis.

This mechanism, known as autophagy-dependent cell death occurs when cells undergo hyperactivated autophagy. Normally, autophagy regulates normal metabolic processes and breaks down and recycles ...

Some of the different types of programmed cell death (PCD) include necroptosis, pyroptosis, apoptosis, and autophagy. Recent studies have provided a better understanding of the mechanisms ...

However, cell death was not inhibited by inhibitors of the other types of PCDs. Hence, they ruled out autophagy, necroptosis, and apoptosis, confirming that paraptosis is a major PCD pathway ...

Impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the obesity paradox.

Autophagy (“self-eating”) is the process through which parts of the cell are degraded in the lysosome. Elucidation of the key genes essential for autophagy — originally identified in yeast ...

Cells use a variety of programmed cell death mechanisms to maintain homeostasis through cellular self-destruction, including apoptosis, necroptosis, and pyroptosis. Elina is a PhD candidate at the ...