Boehringer Ingelheim has started a proof-of-concept trial of a drug that could offer the first oral treatment for geographic atrophy (GA), a major cause of irreversible sight loss that affects ...

Compared with placebo, ATH434 demonstrated a statistically significant 48% slowing of clinical progression (based on UMSARS score) at the 50mg dose at week 52. The Food and Drug Administration ...

The thymus is essential for a healthy immune system, but the causes of age-related thymic atrophy remain a mystery. Scientists have developed approaches for thymic regeneration, but the effects ...

Astellas confirmed today that it will withdraw its EMA filing for avacincaptad pegol as a treatment for eye disorder geographic atrophy (GA), based on feedback from the EU regulator. It is a major ...

Vulvovaginal atrophy is a frequently neglected symptom of menopause. While an estimated 10–40% of women are affected by the progressive symptoms of vaginal dryness, irritation, itching ...

We discovered the function of the thymus and made key findings on the function of the two main subsets of lymphocytes, T cells and B cells. This was the fundamental basis for modern immunology.

According to a 2023 study in 72 postmenopausal women, using a vitamin E vaginal cream for 8 weeks helped significantly improve symptoms of vaginal atrophy, which is a condition characterized by ...

Elevated cerebrospinal fluid tau (total and phosphorylated) Decreased metabolism in temporal and parietal cortex on 18flurodeoxyglucose positron emission tomography Atrophy on magnetic resonance ...