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“We were very surprised by the extent to which the mice improved.” The results, however, need to be replicated in humans before researchers know whether they can lead to new therapeutics for people ...
The parallel rod floor test is a new model of ataxia in mice. It allows the simultaneous measurement of ataxia and locomotor activity. This protocol is designed for researchers examining ethanol ...
Scientists report a significant step toward combatting two degenerative brain diseases that chip away at an individual’s ability to move, and think. A targeted therapy developed by scientists at ...
Cerebellar rhythm loss due to climbing fiber regression is a shared pathophysiology of motor deficits across cerebellar ...
Nerve Disorder In Mice And Men Linked To Mutated Gene Date: October 13, 2003 Source: University Of Michigan Health System Summary: In a discovery that reinforces the importance of the mouse to ...
Antisense drugs reverse ataxia, ALS symptoms in mice By Amirah Al Idrus Apr 13, 2017 11:02am amyotrophic lateral sclerosis antisense Duchenne muscular dystrophy (DMD) neurodegenerative diseases ...
Baudry's team started testing whether the knockout mice had ataxia by tracking their balance when placed on a rotating rod. "We had never looked at the cerebellum in our mice before," says Baudry.
Baudry's team started testing whether the knockout mice had ataxia by tracking their balance when placed on a rotating rod. "We had never looked at the cerebellum in our mice before," says Baudry.
ANN ARBOR, MI – In a small town on Grand Cayman Island in the Caribbean, people are living with a serious neurological disorder, called Cayman ataxia, found nowhere else in the world. People ...
To model ataxia, the team selectively silenced Purkinje cells in mice, which caused ataxia-like motor impairments. 5 “We're using possibly what I think is one of the cleanest ataxia models that is ...
New research from Baylor College of Medicine scientists shows that a combination of deep brain stimulation (DBS) and exercise has potential benefits for treating ataxia, a rare genetic ...