Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and ...

A targeted therapy developed by scientists at University of Utah Health slows the progression of a condition in mice that mimics a rare disease called ataxia. In a parallel collaborative study, led by ...

Other measures of ataxia also force the animal to move, including the balance beam, which scores hind paw slips from the beam as mice traverse it 2. Some animals stop moving during this test ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

University of Utah scientists found that antisense drugs reversed symptoms in mouse models of ataxia and amyotrophic lateral sclerosis. Ataxia, a rare neurodegenerative disease characterized by a ...

4 “From there, the idea was, first, looking in another mouse model,” Salazar said. “And also trying to unravel a little bit of the cellular mechanisms that were at play here.” To model ataxia, the ...

Further investigations in ataxia mouse models confirmed that CF degeneration leads to disruptions in cerebellar frequency, ...

Mice with Kcnj10 deletions became dehydrated, with definitive evidence of renal salt wasting. Mutations in KCNJ10 cause a specific disorder, consisting of epilepsy, ataxia, sensorineural deafness ...

Well-timed exercise programs may slow the progression of Friedreich's ataxia, which robs patients of their ability to walk, new research suggests. A top exercise researcher at the University of ...

In addition, the study reports that stimulating mice with early-stage ataxia showed the most dramatic improvements. These and other findings, published in the journal Nature Communications, provide ...