a potent Selective Estrogen Receptor Modulator (SERM) for estrogen receptor inhibition, to significantly reduce interval breast cancer in women identified as high-risk through advanced ...

SPOKANE COUNTY, Wash. – Spokane County is facing a significant challenge with a 300% increase in overdoses since 2018. Dr. Veena Singh from the Spokane County Medical Examiner's Office ...

Ulipristal (see Figure 1 below) is another derivative of 19-norprogesterone that functions as a selective progesterone receptor modulator (SPRM) with both agonistic and antagonistic effects on the ...

Selective estrogen receptor modulators (SERMs) and selective estrogen receptor downregulators (SERDs) are types of antiestrogen therapy for breast cancer. These medicines block estrogen ...

A phase 1b, open-label, multicenter study of xaluritamig in patients with biochemical recurrence of prostate cancer after definitive therapy. Evaluation of circulating kidney injury marker-1 (KIM-1) ...

Transneural Therapeutics Inc. has described 5-HT2A receptor modulators reported to be useful for the treatment of depression, anxiety, substance abuse and dependence, and headache.

Bempikibart is a fully human interleukin-7 receptor alpha (IL-7Rα ... originally known as AMG 986 and later as BGE-105 before it was renamed azelaprag. Morgan Stanley analyst Jeffrey Hung ...

Excessive caffeine, amphetamines, laxatives, diuretics, steroids, and selective androgen receptor modulators (SARMS)—they’ve all turned up in supplements available to consumers. Even if an ado ...

In these cancers, estrogen can bind to receptors on cancer cells, fueling their growth and spread. Treatments for estrogen-dependent cancers often focus on reducing estrogen levels or blocking ...

Brabus Rocket GTS shooting brake is based on the AMG SL 63 S E Performance Plug-in hybrid powertrain delivers 986 hp and 1,195 lb-ft of torque Production is limited to 25 units Brabus is a German ...

Brabus created a wild-looking shooting brake based on the Mercedes-AMG GT63 S E Performance. Called the Rocket GTS, the shooting brake beefs up the hybrid powertrain to 986 horsepower and 1195 ...