In the field of medicinal chemistry, heterocyclic compounds play an essential role by displaying different biological activity. Five-membered ring containing heterocycles always attracted researchers ...
During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner. Many ...
There is an urgent need for the discovery of new drugs against infectious diseases and cancer. Globally, infectious diseases are prevalent, with pathogens constantly evolving, leading to a rise in ...
Taking aspirin was first linked to a lower risk of colorectal cancer in 1988, but the research into its anti-tumour potential ...
HOPA OCC’s practice-based tools for oncology practices has the potential to improve practice adherence…by using the OAA baseline assessment, facilitate enhanced communication between patients and ...
These cancers are, however, quite sensitive to anticancer drugs such as poly (ADP-ribose) polymerase inhibitors (PARPi). When successful, these cancer treatments cause enough DNA damage to trigger ...
A new study on the genetic causes of the PTEN Hamartoma Tumour Syndrome (PHTS) has found that inhibitors of the PI3ka pathway, commonly used as anticancer drugs, are also effective against this ...
has allowed them to generate the first mouse model of PHTS-related vascular malformations and use it as a benchmark to study the effects of two anticancer drugs known to counterbalance PI3K action ...
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