New studies show that astrocytes, long thought to be support cells in the brain, are crucial intermediaries for relaying messages to neurons.

The phone number used in the Signal chat could also be found in a variety of places, including on social media and a fantasy sports site. By Helene Cooper Julian E. Barnes Eric Schmitt and ...

In addition, a trial-in-progress poster on SUPRAME, the ongoing Phase 3 ... T-cell receptor T-cell therapy (TCR T) that targets PRAME, an intracellular protein displayed as a peptide antigen ...

Tumor antigens are captured and displayed by antigen processing and presentation machinery (APM) on the cell surface by HLA ... SCCs show a 49.3% objective response rate to PD-1 therapy, while ...

Acellular artificial antigen ... signal 2') and cytokine release ('signal 3'). Nanoengineering Approaches for Next-generation aAPCs Most current-generation aAPCs employ static isotropic ...

The effect of hβ2m on the presentation of peptides derived from endogenous antigen was assessed by measuring ... and data compiled from independent experiments (n = 3) are plotted (H). For each ...

The tumor microenvironment, tumor immunogenicity, antigen presentation ... cell receptor recognition of corresponding antigens on major histocompatibility complexes (MHCs) expressed by ...

Several steps are involved in this process, including: 1) peptide generation and trimming in the proteasome; 2) peptide transport; 3) assembly of the MHC class loading complex in the endoplasmic ...