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Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...
Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of ...
Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.
EpiVax, Inc. announces a new study published in Frontiers in Immunology unveiling the impact of peptides known as "Tregitopes ...
note the epitope the antibody was raised against and confirm it’s within the domain of interest. Fixation methods can alter an antigen as well, and permeabilization or antigen retrieval treatments may ...
Determining how to predict the antibody-antigen interactions was the biggest ... it could produce 3D structures for more than just one dominant epitope. The predictions were validated against ...
and epitope-optimized antibody–drug conjugates, to bispecific antibodies and chimeric antigen receptors for cell-based therapies. RubrYc’s collaboration model includes options for co-discovery ...
YUMAB uses libraries of close to germline origin, but highly diverse antigen ... whole antibody-discovery process in vitro and bypassing animal immunization, YUMAB eliminates potential epitope ...
In the landmark Amgen v. Sanofi case (previously covered here), the Supreme Court affirmed that patent claims drawn to a genus of ...
AK0610 is engineered from an antibody isolated from a recovered infant and targets the pre-fusion F protein of RSV. It has a unique viral antigen binding epitope and a new mechanism of action.
Three doses of COVID-19 mRNA vaccination induce long-lasting antibody and memory B-cell responses, according to a study of ...
The antibody 7E11 binds to the intracellular epitope ... Grimm J (2011) Targeting the internal epitope of prostate-specific membrane antigen with 89 Zr-7E11. J Nuclear Med 52(10):1608-15.