Here, we demonstrate that Drosophila malignant epithelial tumors show a similar reduction in ecdysone signaling, the main steroid hormone pathway. Our analysis of ecdysone-induced downstream targets ...

In a recent population-based study, overall survival of patients with newly diagnosed glioblastoma multiforme (GBM), the most common malignant glioma, was 42.4% at 6 months, 17.7% at 1 year, and 3.3% ...