This manuscript introduces a useful protein-stability-based fitness model for simulating protein evolution and unifying non-neutral models of molecular evolution with phylogenetic models. The model is ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

The global market for peptide-based cancer therapies is rapidly expanding, offering new therapeutic and diagnostic opportunities. Peptides, known for their high specificity and minimized toxicity, ...

Quantum computing has potentially transformative capabilities for analyzing agricultural biological systems with ...

Discover how cystic fibrosis genetics affect inheritance patterns and symptom. Learn about CFTR mutations, testing options, ...

Protein engineering is the conception and production of unnatural polypeptides, often through modification of amino acid sequences that are found in nature. Synthetic protein structures and ...

Venom is a proven source of therapeutic drugs. Now, Los Alamos scientists are using AI to speed up the search for cures.

Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome ...

Livagen peptide, a short-chain molecule derived from thymic tissues, has garnered attention recently for its intriguing ...

Amino acid supplements have soared in popularity in recent years. Social-media influencers peddle them with promises that ...

New research has shed light on how plants precisely control their growth and development, revealing that seemingly similar molecular components fulfill surprisingly different jobs.

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...