Curcumin, a phenolic antioxidant extracted from the rhizomes of turmeric and other Curcuma species, possesses strong ...

Talin is a protein that plays an important role in the immune system by activating integrins, receptors that help cells ...

New studies show that astrocytes, long thought to be support cells in the brain, are crucial intermediaries for relaying messages to neurons.

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of ...

The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

The study is useful for advancing spatial transcriptomics through its novel regression-based linear model ... cells, representing 13 distinct cell types, within the mouse brain cortex, visualizing the ...

We have shown that obexelimab inhibits the phosphorylation of BTK, thereby interfering with BCR signalling. Objectives: The aim of this study is to examine the molecular effects of obexelimab on B ...

Herein, we report that our organoid model contains all relevant epithelial cell types found in the colon. We show that SLE serum stimulation can induce alterations in the expression profile, which are ...

Moreover, fibrosis in scleroderma skin grafts was alleviated by engraftment with unmatched allogeneic hematopoietic stem cells. Mechanistic studies supported a trans-signaling model whereby CD4 ...

Macrophages and macrophage-like VSMCs both assume the roles of a signaling sender and receiver, showing the highest communication capability. T cells acted more as senders, while B cells acted as ...

NMII inhibition by cIIAKO did not affect B-cell spreading on PLB but delayed B-cell contraction and altered BCR ... of NMII in BCR signaling utilizing GFP-NMIIA transgenic mice and a partial ...