View software available in the Integrated Systems Biology and AI — Tailored Pharmacology and Precision Medicine Lab led by Hu ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

Researchers at the University of Colorado Anschutz Medical Campus have uncovered a critical, previously underappreciated role ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

This important study shows that nutrient stress emanating from the microenvironment induces metabolic vulnerabilities in pancreatic ductal adenocarcinoma (PDAC). Using a combination of cell-based and ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

although both papers suggest that glypicans may interact with Hh on the cell surface and then internalize together, understanding how GPC3 and Dlp have opposite roles in Hh signalling requires ...

The US regulator has approved Aucatzyl (obecabtagene autoleucel or obe-cel) for the treatment of adults with relapsed or refractory B-cell precursor ALL based on the results of the phase 2 FELIX ...

New research from the Craig Thompson Lab offers a closer look at the transcriptional activators, Yap/Taz, and the role they play in cell growth and macropinocytosis. King, B., Araki, J., Palm, W., & ...

Apr. 16, 2025 — Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of ...