establishing that eoeTCR-4 is specific to milk. An examination of the RNA/TCR sequencing data further found the highest proportion of milk-expanded clones and most of the cells that expressed ...

2025), and long-read RNA sequencing (Pryszcz et al ... genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation. Genome Res (this issue ...

“The discovery of messenger RNA originated with the work of ORNL biologists and chemists in the 1950s, using techniques developed during our work on the Manhattan Project,” said Paul Langan, associate ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation ... whole-genome bisulfite sequencing on freshly isolated ...

Get Instant Summarized Text (Gist) RNA sequencing has been clinically validated for whole-transcriptome analysis, enhancing genetic diagnostics for Mendelian diseases. This test, developed at ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

All raw and processed RNA sequencing data sets have been deposited to the Gene Expression Omnibus database with a specified accession number (GSE260500). The materials that support the findings of ...

Such approaches typically do not allow inference of allele-specific expression of individual gene isoforms, result in less robust estimates since they use only RNA-Seq reads that overlap heterozygous ...

Nextflow workflow to process raw RNA-seq data for allele-specific expression analysis. It takes compressed fastq files as input and generates normalized signal tracks and counts of total ("Gall") and ...

More information: Tebbe de Vries et al, Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly, Proceedings of the National Academy of Sciences (2022).