News

Single-cell RNA sequencing of bone metastases from multiple cancer types reveals three distinct immune archetypes
Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not ...
C&EN10d
RNase T1 Variant RV Cleaves Single-Stranded RNA after Purines Due to Specific Recognition by the Asn46 Side Chain Amide
Department of Chemistry, Division of Biochemistry and Molecular Biology, Hamburg University, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany, Institute of Crystallography, Free University of Berlin ...
GEN - Genetic Engineering and Biotechnology News12d
ASGCT 2025: World’s First Patient Treated with Personalized CRISPR Therapy
Treated with an individualized gene-editing therapy that corrects mutations directly on the genome, a patient shows ...
drugtargetreview.com20d
Allele-selective gene editing: a breakthrough in Huntington’s disease treatment
Our development of an allele ... sequence created by the presence of the ‘T’ allele at the rs362331 SNP site, enabling the highly selective targeting that distinguishes healthy from mutant huntingtin ...
C&EN20d
Acoustic Array Biochip Combined with Allele-Specific PCR for Multiple Cancer Mutation Analysis in Tissue and Liquid Biopsy
Institute of Molecular Biology and Biotechnology-FORTH, 100 N. Plastira Str., Heraklion 70013, Greece ...
Healio29d
Sequencing identifies specific milk protein causing eosinophilic esophagitis
establishing that eoeTCR-4 is specific to milk. An examination of the RNA/TCR sequencing data further found the highest proportion of milk-expanded clones and most of the cells that expressed ...