or allele-specific methylation. The authors identified cell-type-specific patterns that provide valuable insights into how epigenetic modifications can influence gene expression and may help ...

These findings could reshape our understanding of gene expression and disease ... further computational and molecular analyses of allele-specific methylation. Its insights may lead to novel ...

Oncolytic adenovirus was engineered for the forced ectopic delivery of peptide-MHC ligand of T cell receptors (TCRs) to ...

In a paper published in Science Bulletin, the research teams led by Professor Shunmin He, Professor Runsheng Chen, and ...

Allele-specific insights: In 34,000 of these regions ... to uncover new regulatory mechanisms underlying imprinted gene expression and to better understand the complex interplay between genetic ...

Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...

A substantial 35.7-kilobase intrachromosomal inversion at the DG1 (Double-Grain 1) promoter drives the upregulation of DG1 expression ... plants carrying the DG1 allele showed a slight decrease ...

They started by checking whether the high number of COVID hospitalizations in certain Italian provinces could be associated with specific ... But the expression of HLA-B*49 allele emerged as ...

We took advantage of single-cell expression information to identify hundreds of genes with allele-specific effects on expression noise. We used cell-cycle stage classification to map 20 loci that ...