However, hydrophilic groups screen charge, and as such can reduce cell uptake and transfection efficiency. We report the effect of embedding zwitterionic sulfobetaine (SB) groups in cationic comb ...

† School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798 Singapore ‡ Center for Biomimetic Sensor Science, Nanyang Technological University, RTP/XF-06 ...

Inherent limitations in triple transfection are elucidated. Iterations of AAVPureMfg are developed with new plasmid structure design and reduced plasmid demand. AAVPureMfg substantially improves rAAV ...

We are grateful to Dr. Huw Jones and Ms. Caroline Sparks (Rothamsted Research, UK) for providing Agrobacterium tumefaciens AGL1 pAL154/pAL156 and useful suggestions. We also thank Andréa Morás and ...