In mice, mucin-domain glycoproteins on blood vessels wane with age ... in mucin-domain glycoproteins contributes to peripheral immune cells infiltrating the aging brain. Loose Junctions? Normally, ...

A recent study published in the journal Nature showed that the dysregulation of the brain endothelial glycocalyx layer impairs the blood-brain barrier (BBB) in disease and aging. The BBB forms a ...

The study shows that boosting mucin-type O-glycosylation in aged mice reinforces the blood-brain barrier and improves memory, ...

From sweltering hot summer days to frigid winter nights, many people can experience exacerbations in respiratory symptoms of ...

Now Stanford researchers have identified how the breakdown of a sugary layer in the blood vessels that feed the brain could result in aging related ... that layer in mice using gene therapy ...

When mucin was reintroduced to the mice, neuroinflammation dropped ... has a major effect on the brain – both negatively in aging, when these sugars are lost, and positively, when they are ...