Absence of cysteine in mice coaxed fat-storing cells to burn energy, causing weight loss and offering potential therapeutic ...

Beta-adrenergic signaling mechanisms are of central importance to cardiovascular health and disease. Modulation of these pathways represents an important pharmacologic approach to the treatment of ...

The addition of β-adrenergic receptor antagonists to a medical regimen for heart failure that includes angiotensin-converting enzyme (ACE) inhibitors as background therapy has been associated ...

Notably, the α 2a-adrenergic receptor is expressed in brain regions involved in pain modulation, and α 2a-adrenergic agonists (i.e., drugs that activate this receptor can alleviate chronic and ...

A drug that can be taken orally could soon rival the likes of Ozempic for treating type 2 diabetes and obesity, according to a new study. Although its efficacy hasn't yet been tested in humans, the ...

Using inhibitors of different subtypes of adrenergic receptors—α1-, α2-, and β-ARs—the scientists found that NE shushing synapses required only α1-ARs. This surprised them at first, because engagement ...

The adrenaline receptor studied is a member of the G protein-coupled receptor (GPCR) family, and this family is the target of one-third of all Food and Drug Administration (FDA)-approved drugs.

Centhaquine (Lyfaquin®) is an adrenergic agent that increases cardiac preload by activating alpha2B adrenergic receptors to increase venous blood return to the heart and decreases cardiac ...

Researchers from Centro Nacional de Investigaciones Cardiovasculares found stimulation of the beta-3 adrenergic receptor in heart cells helps protect and prevent heart failure from aortic ...

Gemtesa works directly on the beta-3 adrenergic receptors in the bladder muscle. Receptors are like doors that require a chemical “key” to open them and make reactions happen in the body.