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In turn, the cytoskeleton relies on a type of actin protein, called filamentous or F-actin. It forms networks of thin, flexible filaments that affect the shape, stiffness, and movement of cells.

“The actin cytoskeleton dictates the shape and polarity of a cell and is essential in numerous and diverse fundamental processes including cellular division, motility, phagocytosis, organelle ...

More information: Françoise Boismal et al, Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging, Aging (2024). DOI: 10. ...

This important study provides convincing evidence implicating two transcription factors in the regulation of the actin cytoskeleton that shapes the mechanosensory hair bundles of the inner ear's hair ...

Calpain-mediated cleavage of actomyosin cytoskeleton further activates αIIbβ3 integrin ... COTL1 (coactosin-like protein 1) is a member of the ADF (actin depolymerizing factor)/cofilin family that ...

Rac1 activation re-designs the actin cytoskeleton leading to dynamic actin driven remodeling of membrane protrusion and a switch from filopodia to lamellipodia. The reinforced cytoskeleton leads to an ...

Cell shape and transport within the eukaryotic cell are also based on an extensive cytoskeleton ... cells also contain an extensive network of actin filaments thought to be unique to eukaryotic ...

Abstract: Actin cytoskeleton morphology is able to affect and reflect the cellular mechanical properties. However, due to the lack of efficient approaches to quantifying actin cytoskeleton and ...

Briefly, RABV changes the gene expression of essential cytoskeleton related proteins, depolymerizes actin and microtubules ... the proteolytic breakdown of MAP-2 and neurofilaments by calpain in ...