and the actin cytoskeleton. Figure 1: Turnover of talin at adhesions is reduced in the absence of calpain 2. Figure 2: A single point mutation in talin renders it resistant to calpain proteolysis ...

The calpain system is important in cancer biology, particularly during cytoskeleton remodelling, cellular migration and invasion, and its role in modulating the invasive potential of cancer cells ...

these filaments create various superstructures that together make up the actin cytoskeleton. The actin cytoskeleton has the functions of maintaining cell shape, generating cell motility, establishing ...

New research from the Sainsbury Laboratory at the University of Cambridge has shed light on how plants precisely control ...

Within this laboratory, the "Cytoskeleton and Cancer Progression" research group, led by Dr. Clément Thomas, focuses in particular on the actin cytoskeleton and related signaling pathways in the ...

The actin cytoskeleton is a dynamic network made up of actin polymers and associated actin binding proteins. The actin cytoskeleton was originally isolated as a component of the actomyosin complex ...

The role played by the actin cytoskeleton of these compartments and how it responds in the presence of beta-amyloid peptides, the component most commonly associated with Alzheimer's, have been ...

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

Imagine a dark room packed full of furniture. Now imagine moving through it to get to the other side, using only your toe tips for guidance. While it may seem challenging (or unspeakably tedious ...

In this recent study, the researcher and her team analyzed the role of gamma-actin—one of the components of the cytoskeleton—in the organization of junctions between cells, and discovered that ...

The actin cytoskeleton provides force for a large number of cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin ...