Joint Press release from Bambino Gesù Children’s Hospital, Rome; Department of Biochemistry and Gurdon Institute, University ...

Importantly, the team found that mutations associated with neurological conditions like autism and schizophrenia can ...

The Best Illusion of the Year contest offers researchers, and participants, an opportunity to explore the gaps and limits of human perception.

The assembly and disassembly of actin filaments are processes regulated by a large number of actin-interacting proteins, and maintenance of the actin cytoskeleton is “highly susceptible to ...

This valuable study further discloses the function of LRRK2 in BDNF-dependent synaptic processes in identifying postsynaptic actin cytoskeleton as a convergent site of LRRK2 pathophysiological ...

We conclude that BDNF stimulation engages LRRK2 into actin cytoskeleton dynamics through physical association with actin-related proteins. This stimulus-dependent function may be relevant at the ...

The coordinated action of the different cytoskeletal polymers--microtubules, actin filaments and neurofilaments-- is essential for the establishment, remodeling and maintenance of neuronal ...

Porcine brain Arp2/3 complex, human GST-tagged N-WASP VCA domain, rabbit skeletal muscle actin, and ATP were purchased from Cytoskeleton. Tris base, CaCl2, TCEP, NaCl, KCl, MgCl2, and poly-L-lysine, ...

CHRFAM7A modifies the actin cytoskeleton to a more dynamic and stiffness resistant state in an α7nAChR dependent manner. CHRFAM7A may facilitate neuronal adaptation to changes in the brain environment ...

The new research findings show that filamentous actin, a component of the cytoskeleton, interacts with the androgen receptor directly in the cell nucleus and strengthens its effect.