For this reason, this matter has recently brought a lot of attention for the development of drugs targeting the BCR signaling pathway. Fostamatinib disodium is the first Syk inhibitor available ...

2020). Additionally, EVs have the remarkable capacity to induce modifications in gene expression and several signaling pathways within recipient cells, subsequently resulting in profound alterations ...

In solid organ transplantation, especially renal transplantation, for the induction of immune tolerance, accumulating evidence has revealed that Regulatory B cells (Breg) play a crucial role in ...

Mouse cells were incubated with monoclonal rabbit anti-p62 1:500 (clone D10E10) (Cell Signaling Technology ... with the generation of a self-reactive or otherwise dysfunctional BCR. We found that in ...

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