Washed resin was poured into a glass column, and receptor was eluted in 0.1% DDM, 0.03% CHS, 20 mM HEPES pH 7.5, 0.75 M NaCl and 250 mM imidazole. Atropine sulphate and acetylcholine ...

Autoantibodies specific for nicotinic acetylcholine receptors in the autonomic ganglia are potentially pathogenic and may serve as serologic markers of various forms of autoimmune autonomic ...

More information: CI Wolfe et al, Muscarinic Acetylcholine M2 Receptors Regulate Lateral Habenula Neuron Activity and Control Cocaine Seeking Behavior, The Journal of Neuroscience (2022). DOI: 10. ...

The latter is a neurotoxin that acts as a nAChR antagonist, directly competing with acetylcholine (i.e., a neurotransmitter that binds to nicotinic receptors). Moreover, a molecular mechanics ...

To determine the correlation between SARS-CoV-2 and nicotinic acetylcholine receptors (nAChRs), the researchers studied a panel of co-crystal structures along with the neurotoxin binding motif ...

In myasthenia gravis, abnormal antibodies reduce the number of receptors for acetylcholine on muscle cells. You need acetylcholine receptors for your muscles to function normally. The antibodies ...

Katyal N, Govindarajan R, Goyal N, et al. Ravulizumab use for acetylcholine receptor-positive generalized myasthenia gravis in clinical practice. Front Neurol . 2024;15:1378080. doi:10.3389/fneur ...

It alleviates the symptoms brought on by nerve gas exposure by blocking the acetylcholine receptors. That way, even though the chemical attack causes an overabundance of acetylcholine in a victim ...

Researchers have found that blocking certain acetylcholine receptors in the lateral habenula (LHb), an area of the brain that balances reward and aversion, made it harder to resist seeking cocaine in ...