However, Olfr78 was unchanged in EC cells after estrogen treatment. Preincubating female intestinal organoids with estrogen and treating them with acetate (OLFR78 ligand) significantly increased ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

The Interdisciplinary Genitourinary Cancer Forum 2025, held between June 19 – 21, 2025 held in St. Petersburg, Florida, United States, was host to the Prostate Cancer Session 7: Non-metastatic ...

Fit-ligand is a computational algorithm that enables accurate modeling of multiple conformational states of ligands in X-ray crystallography and cryo-electron microscopy (cryo-EM).

Within each (A or B) subclass, receptor-ligand interactions are highly promiscuous and in vivo interactions likely occur where a receptor and ligand of the same subclass are co-expressed.

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Tocopheryl acetate is a form of vitamin E that’s often found in skin care products and dietary supplements. Learn about its potential benefits and risks.

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A novel metal-organic framework with one-dimensional channels {[Cd(3)(CH3COO)2(H2O)2] (CH3CN)x(CH3OH)y} (5), based on conformationally restricted linear 4,4′-bis(1-imidazolyl)biphenyl (3) and cadmium ...

Ligand-Exchange Routes to Second-Generation Ru–Iodide Complexes: (a) HII-I2 Catalysts; (b) CAAC Catalysts Within the corresponding CAAC catalysts, we examined the Hoveyda-class complexes of C1Ph and ...

Ligand Pharmaceuticals, Inc. is a biopharmaceutical company, which engages in the development and acquisition of technologies that help pharmaceutical companies to discover and develop medicines ...