Aiyuk signed a lucrative new deal with the 49ers last offseason. He played in seven games, catching 25 passes for 374 yards.

San Francisco 49ers wide receiver Brandon Aiyuk reportedly could start the regular season on the reserve/physically unable to ...

From 2019-2023, the 49ers won 54 regular-season games -- only the Packers won more games among NFC teams -- and went to two ...

Christian McCaffrey's injury woes tripped up the San Francisco 49ers last season. Can they overcome any absence from him this ...

San Francisco 49ers running back Christian McCaffrey dealt with some pretty significant injury issues early in his career ...

Despite an injury-riddled 2024 season, San Francisco 49ers star running back Christian McCaffrey is still considered one of ...

49ers fullback Kyle Juszczyk believes the team is returning to form in 2025, with RB Christian McCaffrey looking "incredible" ...

San Francisco struggled with injuries to several star players last season, but now Kyle Shanahan’s crew is healthy and ready to compete for a championship.

Christian McCaffrey's injury woes tripped up the San Francisco 49ers last season. Can they overcome any absence from him ...

Brock Purdy was asked would he rather win one Super Bowl in his career with the 49ers or win three with the Seahawks: “I’m ...

Kittle chugged a beer and made a birdie during a strong start in the scramble preceding the American Century Championship ...

While Jerry Rice has guarded optimism the 49ers can rally around a young defense, he insists that Brandon Aiyuk should not be ...