Beyond established roles in collagen biosynthesis, hypoxic signaling and fatty acid metabolism, recent reports have now revealed roles for human 2-oxoglutarate–dependent oxygenases in histone ...

In the past two decades, iron and 2-oxoglutarate dependent (Fe/2OG) enzymes have been discovered to catalyze an ever-growing array of novel oxidative modifications of small molecules, thereby ...

Institute for General Microbiology, Christian Albrechts University, Kiel, Germany Center for Synthetic Microbiology (SYNMIKRO) Research Center and Department of Chemistry, Philipps-Universität Marburg ...

FIGURE 2. Pyruvate to AC conversion ... and is linked to the some neurodegenerative diseases such as AD and Huntington’s disease), and 2-oxoglutarate (a TCA cycle intermediate that plays a vital role ...

Analysis of transcriptional control (HIF and NF- B transcription factor family), chromatin and epigenetics as well as novel targets for 2-oxoglutarate dependent dioxygenases, including JmjC-containing ...

How do you open Overwatch 2 loot boxes? Loot boxes were an Overwatch 1 staple, so it’s no surprise that fans were a little disappointed when the random reward system was removed from the sequel.

Nintendo Switch 2 is finally confirmed. After literal years of unverified rumors, dubious leaks and copious amounts of online speculation, Nintendo has lifted the lid on its next-generation ...

TL;DR: AMD is bringing in a next-gen AFMF, version 2.1, that's expected to launch with its RX 9070 GPUs, benefiting from enhanced image quality while still working with existing GPUs - it won't be ...

Read full article: Driver, dog OK after tornado flips big rig in Seminole County A closer look at a home destroyed in the Longwood area by an EF-2 tornado. King sheets, commoner prices ...

The company generated $2.15 per share of non-GAAP earnings in the fourth quarter (which ended Dec. 31) and had $24.8 billion in free cash flow. This means Alphabet generates plenty of cash without ...

Sledgehammer-wielding thieves who smashed their way into Blenheim Palace managed to steal a £2.8m gold toilet in just five minutes, a court has heard. The toilet, an artwork by Italian artist ...