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Journal of Nuclear Medicine1d
Granzyme B PET Imaging Predicts Response to Immunotherapy in a Diet-Induced Obesity Model of Breast Cancer
The effects of obesity on cancer treatment efficacy remain unclear, as both beneficial and detrimental modulations of the tumor immune microenvironment have been reported. We compared 68Ga-NOTA-GZP ...
snmjournals.org3y
Appropriate Use Criteria for the Use of Nuclear Medicine in Musculoskeletal Infection Imaging
The value of nuclear medicine imaging for diagnosing infections, was first recognized nearly 50 y ago (1). The 3-phase bone scan was for many years the radionuclide test of choice for musculoskeletal ...
snmjournals.org12mon
Preclinical Evaluation of Anti-uPAR Antibody as a Radiolabeled PET Imaging Candidate in Solid Tumors
Introduction: MNPR-101 is a humanized monoclonal antibody to the urokinase plasminogen activator receptor (uPAR). uPAR expression is elevated in several aggressive cancers but rarely if at all ...
snmjournals.org3y
First-in-Humans Evaluation of a PD-L1–Binding Peptide PET Radiotracer in Non–Small Cell Lung Cancer Patients
Treatment of non–small cell lung cancer (NSCLC) has advanced considerably over the past 40 y. In addition to the advent of molecularly targeted therapies, inhibition of immune checkpoints using ...
snmjournals.org1y
Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis
Rheumatoid arthritis (RA) affects 0.5%–1% of the global population, making it the most common inflammatory arthropathy worldwide (1). It is a complex autoimmune disease characterized by chronic ...
snmjournals.org22d
A Vision for Gastrin-Releasing Peptide Receptor Targeting for Imaging and Therapy: Perspective from Academia and Industry
Journal of Nuclear Medicine May 2025, jnumed.124.269444; DOI: https://doi.org/10.2967/jnumed.124.269444 ...
snmjournals.org22y
Patterns of Lymphatic Drainage from the Skin in Patients with Melanoma
An essential prerequisite for a successful sentinel lymph node biopsy (SLNB) procedure is an accurate map of the pattern of lymphatic drainage from the primary tumor site in each patient. In melanoma ...
snmjournals.org1y
Sequencing of Somatostatin-Receptor–Based Therapies in Neuroendocrine Tumor Patients
Most well-differentiated neuroendocrine tumors (NETs) express high levels of somatostatin receptors, particularly subtypes 2 and 5. Somatostatin analogs (SSAs) bind to somatostatin receptors and are ...
snmjournals.org15d
Routine Dosimetry: Proceed with Caution
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snmjournals.org15d
Uncommon Anomalous Biodistribution of
Journal of Nuclear Medicine May 2025, jnumed.125.269614; DOI: https://doi.org/10.2967/jnumed.125.269614 ...
snmjournals.org15d
The Australian National Total-Body PET Facility—A Shared Resource and Risk Model for Implementing Total-Body PET
Journal of Nuclear Medicine May 2025, jnumed.125.269859; DOI: https://doi.org/10.2967/jnumed.125.269859 The introduction of total-body PET, or long–axial-field-of ...
snmjournals.org8d
Published Ahead of Print
Absorbed Dose–Response Relationship in Patients with Gastroenteropancreatic Neuroendocrine Tumors Treated with [177 Lu]Lu-DOTATATE: One Step Closer to Personalized Medicine Prediction of 177 ...