How did eukaryotic organisms become so much more complex than prokaryotic ones, without a whole lot more genes? The answer lies in transcription factors. Experiments have shown that TFs can bind ...

In eukaryotes, termination is more complex and involves additional factors that help to release the RNA polymerase and the newly synthesized RNA molecule. mRNA is the most common type of RNA produced ...

He then did a three-year post-doctoral position at the University of Portsmouth investigating eukaryotic transcription factors involved in blood development. In 2000, he moved to the Animal Health ...

Chromatin remodeling is an important mechanism of regulating eukaryotic gene expression, which makes tightly condensed DNA accessible to various regulatory factors, such as transcription factors ...

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna. In addition to exporting materials out of the ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...