C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic information from DNA to messenger RNA (mRNA). As there are more than 700 ...

The monocytic leukemia zinc-finger protein (MOZ) gene is rearranged in t(8; 16)(p11; p13) and inv(8)(p11q13) associated with acute myeloid leukemia. The other fusion partners involved are CBP and ...

Their findings center on ZIP4, a protein that transports zinc throughout the body and sets off a cascade of events that drive tumor growth. About half of all malignant brain tumors are glioblastomas, ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair, ...

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After you eat a meal, zinc is taken up by the cells of your body. Inside each cell, zinc binds to proteins to support their structure and function. Researchers estimate that up to 10% of all proteins ...

Hangzhou Polymed Biopharmaceuticals Inc. has divulged molecular glue degraders comprising cereblon (CRBN) binding agents covalently bound to a zinc finger protein Helios (IKZF2)-targeting moiety ...

Their findings center on ZIP4, a protein that transports zinc throughout the body and sets off a cascade of events that drive tumor growth. In a study published Wednesday in the Proceedings of the ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) After you eat a meal, zinc is taken up by the cells of your body. Inside each cell ...