Zinc finger nucleases are designed to be like heat-seeking missiles, precisely targeted to find and cut specific sequences of DNA. Occasionally, however, they may snip the wrong spot, causing ...
Understanding of the DNA-binding characteristics of zinc-finger protein transcription factors has made it possible to design ZFPs to bind to specific target sequences and these designed ZFPs have been ...
Figure 1 Left shows: Two zinc fingers in the DROSHA crystal structure. Right: A partial structure of the Microprocessor complex. Disclaimer: AAAS and EurekAlert! are not responsible for the ...
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