Shortly after this publication, Bogdanove struck up a collaboration with Daniel Voytas, a plant geneticist at the University ...

C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...

Zinc finger nucleases are designed to be like heat-seeking missiles, precisely targeted to find and cut specific sequences of DNA. Occasionally, however, they may snip the wrong spot, causing ...

Shanghai Henlius Biologics Co. Ltd. has synthesized histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) ...

Another result of this research are zinc finger nucleases. These artificial enzymes consist of a sub-unit that recognizes the desired DNA sequence, and a DNA-cutting part of a restriction enzyme.

Similarly of dual use is genetic engineering, most commonly referring to Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology that evolved from Zinc Finger Nucleases (ZFN ...

Sangamo believes that its zinc finger epigenetic regulators are ideally suited to potentially address devastating neurological disorders and that its capsid discovery platform can expand delivery ...

Figure 1 Left shows: Two zinc fingers in the DROSHA crystal structure. Right: A partial structure of the Microprocessor complex. Disclaimer: AAAS and EurekAlert! are not responsible for the ...

Proper splicing requires efficient spliceosome assembly. Here the authors reveal that zinc finger protein 207 interacts with the U1 small nuclear ribonucleoprotein to accelerate spliceosome ...

Kangpu Biopharma receives China NMPA’s IND approval for KPG-818 to treat relapsed/refractory multiple myeloma: Hefei, China Saturday, March 1, 2025, 14:00 Hrs [IST] Kangpu Bioph ...