Horizon Discovery provides research tools and services to biopharma and diagnostics companies, from small virtual start-ups to multinationals. The company has developed a suite of functional ...

Aconsortium of 17 laboratories worldwide has presented results contradicting a highly cited study that described a technique to create conditional knockout mice using CRISPR. The preprint, published ...

This is going to help those utilizing more clinically relevant lines because we have, in some instances, seen improvements in the knockout efficiencies when using a synthetic sgRNA format compared to ...

BCL6 knock-out in a DLBCL xenograft induces tumor stasis. Tumor xenografts were established in C.B-17 SCID mice by subcutaneous injection of inducible SU-DHL-4 Cas9 BCL6 and control sgRNA cells.